Chlamydia - an emerging human pathogen

by Sebastian Banhart


Robert Koch Institute

Chlamydiae live inside human epithelial cells and therefore strongly depend on them. During its replication, the bug hijacks the Golgi apparatus (GA) to get access to essential nutrients, especially lipids. By state-of-the-art confocal microscopy, we are investigating this process of subversion. - After several rounds of replicating and reinfecting neighboring cells, Chlamydiae (green) form plaques in a cellular monolayer (nuclei in blue, GA in red) - both beautiful and scary "black holes"...

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